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Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Online ISSN 1827-1820
Percivalle S. 1, Piccinno R. 1, Gnecchi L. 2, Caccialanza M. 1
1 Photoradiotherapy Unit Institute of Dermatological Sciences University of Milan IRCCS Foundation, Ospedale Maggiore Mangiagalli e Regina Elena, Milan, Italy.
2 Unit of Dermatology S. Gerardo dei Tintori Hospital , Monza, Italy
Aim. The treatment of skin carcinomas of the eyelids is still an open question: the objective is to link radical therapy to the conservation of the physiological functions and an adequate esthetic result. To prove the consistency with this objective, we performed a retrospective study on a series of cases enrolled during the period 1976-2004 and treated with radiotherapy.
Methods. A total of 85 patients suffering from 88 epithelial neoplastic lesions of the eyelids were treated with radiotherapy: 48 patients were females, 37 males, aged 38 to 89 years (mean age 71.07). The 88 lesions treated were 86 basal cell carcinomas, 1 squamous cell carcinoma e 1 metatypic carcinoma. Radiotherapy was delivered by contact X-ray therapy (CXRT) according to Chaoul, using a cup-shaped internal eye shield made of an alloy of lead, zinc and nickel to avoid lens damage. The total doses administered ranged from 40 to 65 Gy.
Results. Complete remission was achieved in 86 lesions (97.72%), and 2 basal cell carcinomas relapsed marginally (2.28%). The 5-year cure-rate from the end of radiotherapy (evaluated according to the life-table method) was 96.72%. So far, neither complications nor sequelae to the radiological treatment have been observed.
Conclusions. The excellent therapeutical and esthetic results obtained in this series of patients treated with radiotherapy confirm the reports of the literature and support the choice of dermatological radiotherapy in the treatment of cutaneous carcinomas of the eyelids.