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Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
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Aste N., Loi A. M., Pau M.
Dermatological Clinic, University of Cagliari, Cagliari, Italy
Aim. In Sardinia, cutaneous leishmaniasis has a hypoendemic occurrence rate, affecting some 0.16‰ inhabitants, 0.7‰ in the Province of Cagliari. This study reports the clinical and epidemiological research into cutaneous leishmaniasis in the Province of Cagliari.
Methods. The authors studied all the cases of cutaneous leishmaniasis referred to the Dermatological Clinic of the University of Cagliari in the period from 1989 to 2002. Diagnosis was based on clinical data and the identification of Leishmania in cytological and/or histological specimens. All patients were treated intralesionally with pentavalent antimony salts. During the years under review we observed 71 cases of cutaneous leishmaniasis, 41 males and 30 females, aged between 8 months and 80 years. Sixty patients had single lesions, 11 had multiple lesions. The most affected area was the face.
Results. Clinical diagnosis was always confirmed by direct microscopic examination of samples taken from the lesion and coloured with May-Grunwald-Giemsa which revealed the presence of intra- and extra-cellular protozoans. In 8 cases, Leishmania typing made it possible to isolate Leishmania infantum. All patients recovered fully.
Conclusion. Cutaneous leishmaniasis is still present in Sardinia and the most frequent form is non-ulcerated Oriental sore. Intralesionally-administered pentavalent antimonial compaunds should be considered the treatment of choice.
language: English, Italian