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GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA
A Journal on Dermatology and Sexually Transmitted Diseases
Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Giornale Italiano di Dermatologia e Venereologia 2004 December;139(6):515-9
Scrotal calcinosis: a histopathological study and review of the literature
Mohan H. 1, Aggarwal R. 1, Tahlan A. 1, Thami G. P. 2
1 Department of Pathology Govt. Medical College, Chandigarh, India
2 Department of Dermatology and Venereology Govt. Medical College, Chandigarh, India
Aim. Scrotal calcinosis is an uncommon condition, characterized by firm, painless nodules that are either single or multiple. The etiopathogenesis of calcinosis is disputed. A few have regarded it to be a dystrophic calcification of epidermal/pilar or eccrine duct milia while others deem it to be idiopathic.
Methods. Pathology of 14 cases of scrotal calcinosis, observed from January 1994 to May 2002, is presented in this study. All patients presented with firm, palpable, whitish-yellow, scrotal nodules, with a clinical diagnosis of sebaceous cyst or calcinosis of scrotum.
Results. A definite epithelial lining, or its remnants, surrounded the calcified contents of the cysts in 3 cases. In the remaining, the cysts consisted of partly to completely calcified keratinous material, without a definite epithelial lining. The latter presumably disappeared in due course of time.
Conclusion. We favor dystrophic calcification of the cysts, either epidermal or pilar, as the etiology of scrotal calcinosis.