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GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA
A Journal on Dermatology and Sexually Transmitted Diseases
Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Giornale Italiano di Dermatologia e Venereologia 2004 October;139(5):499-503
language: English, Italian
Two different therapeutic choices in confluent and reticulated papillomatosis
Patrone P., Trotter D., Stinco G.
Department of Clinical and Experimental Pathology and Medicine, Institute of Dermatology University of Udine, Udine, Italy
Confluent and reticulated papillomatosis (CRP) of Gougerot and Carteaud is a dermatosis due to a genetically determined keratinization disorder. The histological examination of the lesions shows hyperkeratosis, papillomatosis and modest epidermic acanthosis. We report 2 cases of subjects affected by CRP: a 17year old male patient presenting extensive lesions localized in the mediosternum, periumbilical and medionuchal regions, and a 13year old female patient with manifestations localized on the nape and prosternum. The first patient was treated with minocycline cp 100 mg/die for 1 month and the second with calcipotriol 0.005% applied twice daily for a period of 3 months. In both cases the histological examination confirmed the diagnosis of CRP and the mycological tests gave negative results. In both cases we obtained remission that persisted during the control visits that followed. What emerges from our experience, also compared with that of other authors, is that calcipotriol or minocycline as many other drugs are active and therefore a therapeutic choice must be made on the basis of the characteristics of the patient and on the extension of the dermatosis.