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Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Online ISSN 1827-1820
Broganelli P., Chiaretta A., Giovannini E., Pippione M.
Department of Dermatology University of Turin, Turin, Italy
We report the case of a 77-year-old man with atrophic scars which had appeared in the last 12 years, always preceded by blisters or by epidermal detachment developing after mild traumas. These lesions were localized in the extensor part of his legs and were asymptomatic. Histological examination and direct immunofluorescence (DIF), performed on skin that had been fractured by incubating in 1M NaCl (DIF Salt-Split), confirmed the diagnosis of epidermolysis bullosa acquisita (EBA). The clinical features classify it as a localized variant. Other examinations made on the patient excluded a systemic involvement. EBA is a rare autoimmune blistering disease that usually begins in adulthood and can manifest itself in the classical presentation or, less often, in inflammatory form, or frequently in the localized Brunsting-Perry-like variant.
language: English, Italian