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GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA
A Journal on Dermatology and Sexually Transmitted Diseases
Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Giornale Italiano di Dermatologia e Venereologia 2004 April;139(2):149-53
language: English, Italian
Clinical study of the efficacy of frequent shampoo use for two childhood scalp conditions: cradle cape and atopic dandruff
Patrizi A., Marzaduri S., Neri I., Medri M.
Department of Clinical and Experimental Medicine Division of Dermatology University of Bologna, Bologna, Italy
Aim. The aim of this study was to evaluate the effectiveness of Cetafil®, a new shampoo for frequent use, in children and infants affected by cradle cape and atopic dandruff.
Methods. We performed a 2-month open label study involving 15 infants aged between 0 and 3 months with cradle cape and 15 children aged between 3 months and 3 years with atopic dandruff. In all patients the scalp was washed with Cetafil® shampoo, at 2 day intervals for 4 weeks then twice weekly for a further 4 weeks. The patients with cradle cape used exclusively this shampoo, while the patients with atopic dandruff applied a 0.05% desonide lotion once nightly every day for 5-7 days and then optionally for only 2 or 3 days. Clinical evaluation at baseline, 2, 4 and 8 weeks included redness, scaling, hair damage and hair loss in both groups and also pruritus in the children with atopic dandruff.
Results. Twenty-seven patients (90%) showed a total resolution of the clinical manifestations after 2 to 4 weeks of treatment. One patient with cradle cape showed mild scaling and 2 children with atopic dandruff still had small areas covered by firm scales at the end of the 2-month therapy. No side effects were registered and no subjective symptoms were reported at the end of the study.
Conclusion. Cetafil® shampoo and desonide lotion are safe and effective medications in the treatment of some pediatric scaly conditions of the scalp.