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GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA

A Journal on Dermatology and Sexually Transmitted Diseases


Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
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Giornale Italiano di Dermatologia e Venereologia 2004 April;139(2):149-53

Copyright © 2004 EDIZIONI MINERVA MEDICA

language: English, Italian

Clinical study of the efficacy of frequent shampoo use for two childhood scalp conditions: cradle cape and atopic dandruff

Patrizi A., Marzaduri S., Neri I., Medri M.

Department of Clinical and Experimental Medicine Division of Dermatology University of Bologna, Bologna, Italy


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Aim. The aim of this study was to evaluate the effectiveness of Cetafil®, a new shampoo for frequent use, in children and infants affected by cradle cape and atopic dandruff.
Methods. We performed a 2-month open label study involving 15 infants aged between 0 and 3 months with cradle cape and 15 children aged between 3 months and 3 years with atopic dandruff. In all patients the scalp was washed with Cetafil® shampoo, at 2 day intervals for 4 weeks then twice weekly for a further 4 weeks. The patients with cradle cape used exclusively this shampoo, while the patients with atopic dandruff applied a 0.05% desonide lotion once nightly every day for 5-7 days and then optionally for only 2 or 3 days. Clinical evaluation at baseline, 2, 4 and 8 weeks included redness, scaling, hair damage and hair loss in both groups and also pruritus in the children with atopic dandruff.
Results. Twenty-seven patients (90%) showed a total resolution of the clinical manifestations after 2 to 4 weeks of treatment. One patient with cradle cape showed mild scaling and 2 children with atopic dandruff still had small areas covered by firm scales at the end of the 2-month therapy. No side effects were registered and no subjective symptoms were reported at the end of the study.
Conclusion. Cetafil® shampoo and desonide lotion are safe and effective medications in the treatment of some pediatric scaly conditions of the scalp.

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