Home > Journals > Giornale Italiano di Dermatologia e Venereologia > Past Issues > Giornale Italiano di Dermatologia e Venereologia 2003 December;138(6) > Giornale Italiano di Dermatologia e Venereologia 2003 December;138(6):513-7





A Journal on Dermatology and Sexually Transmitted Diseases

Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014




Giornale Italiano di Dermatologia e Venereologia 2003 December;138(6):513-7

language: Italian

Topical treatment of chronic pressure ulcers with Ustiosan

Ricci E. 1, Bosio D. 2, Nano M. 3

1 Centro Vulnologico Italiano, Torino,
2 Centro ricerche Biologiche La Carignana, Caselle Torinese,
3 Dipartimento di Fisiopatologia Clinica, Università degli Studi di Torino, Torino


Aim. Chronic pressure ulcers constitute a growing healthcare problem as the number of older persons increases. In Italy an estimated 3-4% of the population will eventually develop a chronic skin lesion. An important part of local treatment to promote skin repair is pain control and elimination of necrotic and infected tissue. This study evaluated the clinical performance of a topical preparation containing lidocaine, procaine and 8-oxyquinoline (Ustiosan®, Kelemata SpA, Turin) in the treatment and management of chronic pressure ulcers.
Methods. This open study used Ustiosan, a topical ointment containing procaine chlorhydrate (0.5%), lidocaine hydrate (0.5%) and 8-oxyquinoline sulphate for the treatment of chronic
pressure ulcers. The study group consisted of 20 outpatients (10 men, 10 women; mean age, 68.7 years; range, 19-91) with normal nutritional status; 18 presented with pressure ulcers, 1 with lower limb venous ulcer and 1 with Martorell’s ulcer of the lower limb.
Results. Healing was achieved in 20% of cases, an extremely promising finding even for such a short observation period. Wound margin recovery was attained in 90% of cases, and pain control was efficacious in 90%.
Conclusion. The results of this study suggest that Ustiosan may be advantageously used as Primary local treatment of uncomplicated chronic skin ulcers, particularly in painful lesions.

top of page

Publication History

Cite this article as

Corresponding author e-mail