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GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA
A Journal on Dermatology and Sexually Transmitted Diseases
Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Giornale Italiano di Dermatologia e Venereologia 2003 October;138(5):409-413
Nevus sebaceous: a review of 73 pediatric cases
Patrizi A. 1, Neri I. 1, Varotti E. 1, Fiorentini C. 2, Landi C. 2
1 Dipartimento di Medicina Clinica Specialistica e Sperimentale, Sezione di Clinica Dermatologica Università degli Studi di Bologna, Bologna
2 Unità Operativa di Dermatologia Ospedale Infermi, Rimini
Aim. Nevus sebaceous (NS) is the most frequent epidermal nevus occurring mainly on the face and scalp.
Methods. In this study a series of 73 NS is presented. All the affected patients were followed up for at least 6 years. We considered the sex and age of patients, the location, morphology, histopathology and evolution of the NS, family history positive for NS and the presence of associated symptoms or developmental abnormalities.
Results. Our 73 patients were 38 boys and 35 girls, first observed at a mean age of 3 years. In 67 patients the lesion was noted at birth and in 54 it remained stable and unchanged during the follow-up. Fifty-five lesions were localized on the scalp, 14 were on the face, 3 on the neck and 1 was on the ear. In 12 cases histopathology confirmed the clinical diagnosis and in 1 case a syringocystoadenoma papilliferum was diagnosed. Family history positive for NS was found in 6 cases. Minimal skeletal or ophthalmologic abnormalities were present in only 3 cases.
Conclusion. In our series NS appears as a congenital, benign, stable lesion, mainly located on the scalp, without sex predilection. We observed 6 familial cases (8.2%). In the literature NS appears as a sporadic tumour, but we can suppose that in some families there is a genetic predisposition to this anomaly. Associated developmental abnormalities were very rare (3 cases of 73) and of slight importance in our case-study in contrast with some data from the literature.