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GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA

A Journal on Dermatology and Sexually Transmitted Diseases


Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
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Giornale Italiano di Dermatologia e Venereologia 2003 October;138(5):363-75

language: Italian

Primary acquired scarring alopecia: classification and diagnostic criteria

Fabbri P., Amato L., Chiarini C., Massi D., Moretti S.

Clinica Dermatologica II Dipartimento di Scienze Dermatologiche Università degli Studi di Firenze, Firenze


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Scarring alopecia (SA) is a group of diseases characterized by permanent hair loss, cutaneous atrophy and sclerosis of variable grade. Two forms of acquired SA have been described: “primary” and “secondary” forms. In the primary acquired SA the inflammation target is the follicle; in the secondary SA the follicle is merely an “innocent bystander”: inflammation affects primarily the interfollicular skin and later destroys the follicle in a non-specific manner. Primary acquired SA may be divided into 2 main groups according to the type of the cell infiltrate: lymphocytic forms and neutrophilic forms. In the lymphocytic forms we include: a) pseudopelade of Brocq; b) lichen planopilaris; c) chronic cutaneous lupus erythematosus; d) central centrifugal scarring alopecia. In the neutrophilic forms: a) folliculitis decalvans; b) tufted folliculitis; c) erosive pustular dermatosis of the scalp; d) dissecting cellulites; e) acne keloidalis. According to the cases studied in the last 10 years at the Department of Dermatological Sciences of the University of Florence, we reported the diagnostic, clinical, histopathological and immunopathological criteria for each of these forms.

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