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GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA
A Journal on Dermatology and Sexually Transmitted Diseases
Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Giornale Italiano di Dermatologia e Venereologia 2002 December;137(6):431-3
Use of hydrolyzed oat proteins bath soak (AVALON*). Clinical experience in 30 children suffering from mild atopic dermatitis
Patrizi A., Neri I., Raone B., Savoia F.
Sezione di Clinica Dermatologica Dipartimento di Medicina Clinica Specialistica e Sperimentale, Università degli Studi di Bologna, Bologna
Background. Recent breakthroughs in the fractionation of traditional oat sources has led to the development of a clear hydrolyzed oat protein which appears to have all the benefits of its colloidal counterpart with less of the problems normally associated with their use.
Methods. A total of 30 children affected by mild atopic dermatitis (14 M, 16 F), aged between 3 months and 11 years, were treated with AVALON* clear Oatmeal oil free bath soak and AVALON* soap daily for 2 weeks.
Patients were instructed to use AVALON* clear bath soak for 15 minutes daily, at approximately the same time every day, for 14 days and all patients were told to use only AVALON* soap to clean during the same period. No other treatment was made.
Each patient was examined at the end of the first and the second week to evaluate severity of itching, burning, erythema, scaling, dryness lichenification and escoriation. All the signs and symptoms were evaluated with a grading scale from 1 to 10. In addition, an overall clinical and patient’s impression was evaluated.
Results. At the end of this trial 5 patients completely cleared, 19 showed a significant improvement and 4 a moderate improvement. No effect was observed in 2 cases. At the week 2 parents referred that the conditions of their children were good or very good in 24 cases. No irritant or allergic adverse effects were reported during the study.
Conclusions. The results obtained confirm that AVALON* clean bath soak and soap after a good possibility in the maintenance treatment of mild atopic dermatitis in children and infants.