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A Journal on Dermatology and Sexually Transmitted Diseases

Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
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Giornale Italiano di Dermatologia e Venereologia 2001 October;136(5):371-87

language: Italian

Vascular anomalies in dermatology

Gelmetti C.

Università degli Studi - Milano Istituto di Scienze Dermatologiche IRCCS «Ospedale Maggiore» di Milano


Vascular anomalies, according to the classification of Requena and Sangueza, can be divided in eight groups of which the first three correspond to vascular malformations and the others correspond to vascular tumors of ISSVA classification inspired by Mulliken. We distinguish therefore: 1) hamartomas (pigmentovascular phacomatosis and eccrine angiomatous hamartoma); 2) malformations (functional malformation [nevus anemicus] and anatomical malformation [capillary: e.g., nevus flammeus; venous, arterious, lymphatic and combined]; 3) dilatation of preexisting vessels (e.g., spider nevus, telangiectasias, angiokeratomas, lymphangiectasias); 4) hyperplasias (angiolymphoid hyperplasia with eosinophilia, pyogenic granuloma, bacillary angioma, verruga peruana, intravascular papillary endothelial hyperplasia, pseudo-Kaposi sarcoma, Mali acroangiodermitis, Stewart-Bluefarb S.); 5) benign neoplasms (with endothelial differentiation [capillary and venules: e.g., benign capillary angioma, cherry angioma, tufted angioma; veins and arteries: e.g., sinusoidal angioma; lymphatics: e.g., benign lymphangioendothelioma]; with glomous cell differentiation: e.g., glomangioma; with pericytic differentiation (hemangiopericytoma); 6) malignant neoplasms (Kaposi sarcoma, cutaneous angiosarcomas with low or high degree of malignancy, glomangiosarcoma); 7) other cutaneous neoplasms with significant vascular component (e.g., angiohistiocytoma with multinucleated cells, angiofibroma, angioleiomyoma, angiolipoma); 8) disorders erroneously considered as vascular neoplasms (e.g., Kimura disease, “benign” and “malignant” angioendotheliomatosis and APACHE syndrome). The most common or interesting forms for the dermatologist are described together with the relative principles of treatment.

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