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Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Online ISSN 1827-1820
Patrizi A., D’Acunto C., Fanti P. A., Neri I.
Università degli Studi - Bologna Dipartimento di Clinica Specialistica e Sperimentale Sezione di Clinica Dermatologica (Responsabile: Prof. C. Varotti)
Basal cell carcinomas (BCC) are slowly growing neoplasms that often develop on sun-exposed sites. In fact, 85% of all BCC appear on the head and neck region, 25 to 30% occurring on the nose alone, which is the most common site. Although BCC is the most common cutaneous neoplasm, only few cases involving the scrotum have been reported. Clinically, the lesions are present as plaques or ulcers and occur preferably on the left side of the scrotum. The average age of onset of scrotal BCC is reported to be 65 years. Whereas metastatic BCC is rare, with a reported incidence of 0.0028 to 0.1%, the incidence of metastases in patients with BCC is 13%. Wide local excision or Mohs micrographic surgery are therefore the most appropriate therapeutic approaches for such lesions. Exposure to oil and its products, radiation therapy, arsenical compounds and chronic dermatitis have been associated with squamous cell carcinomas of the scrotum but not to the BCC. The clinical and histological features of a 41 year old patient with a scrotal BCC histologically diagnosed as a BCC are reported. Clinically this lesion showed the features of a nodular BCC with smooth, shiny surface. The lesion had started only 6 months before consultation. The authors believe that such a clinical picture may represent the initial stages of BCC in younger men.