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GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA

A Journal on Dermatology and Sexually Transmitted Diseases


Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
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Giornale Italiano di Dermatologia e Venereologia 2001 February;136(1):49-53

language: Italian

Monocytic aleukemic leukemia cutis. Report of a case and review of the literature

Muscardin L. M., Sacerdoti G., Villivà N. *, Matera R. *, Pulsoni A. *

Istituto S. Gallicano, IRCCS, Roma Istituto di Ematologia
*Università degli Studi di Roma «La Sapienza» - Roma


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Aleukemic leukemia cutis is a rare condition in which patients have skin lesions containing leukemic cells without evidence of leukemia in peripheral blood and bone marrow. The case of a 75-year-old man, who developed a diffuse papulo-nodular cutaneous eruption specially on the trunk histologically showing an atypical infiltrate of leukemic cells (monocytic cells), without evidence of sistemic disease, is reported. A low-dose Metho-trexate therapy produced a complete remission of the disease, persisting after eighteen months of follow-up.

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