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GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA
A Journal on Dermatology and Sexually Transmitted Diseases
Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Giornale Italiano di Dermatologia e Venereologia 2000 December;135(6):675-7
Treatment of idiopathic hyperhidrosis with botulinum toxin type A
Breit S., Heckmann M., Plewig G.
From the Klinik und Poliklinik für Dermatologie und Allergologie Ludwig-Maximilians Universität - Munchen, Germany
Severe hyperhidrosis may present as a vexing condition for the patient and a therapeutic challenge for the physician. botulinumtoxin-A can specifically inhibit acetyl-cholin-dependent neuromuscular transmission and is used for the relaxation of spastic or dystonic muscles. It can also potently block cholinergic sympathic innervation of sweat glands. Therefore, botulinumtoxin-A has gained recent attention in dermatology as a powerfull treatment modality for circumscribed hyperhidrosis. Intradermal injection of botulinumtoxin-A in the axilla or hands reduces sweating effectively with minimal side-effects. Treatment results are mostly appreciated as “completely satisfying” by the patients. Botulinumtoxin-A offers a fast, safe and highly effective therapeutic option for severe hyperhidrosis.