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Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Online ISSN 1827-1820
Ferrara G., Soscia A. *, Cinelli M. P. *, Delfino M. **, Ayala F. **
A.O. «G. Rummo» - Benevento U.O Anatomia ed Istologia Patologica Università degli Studi «Federico II» - Napoli
* Dipartimento di Scienze Biomorfologiche e Funzionali, Istituto di Anatomia Umana Normale
** Dipartimento di Patologia Sistematica, Clinica Dermatologica
Background. The pathogenetic basis for psoriatic skin lesions is made up of two interacting factors, keratinocytic hyperproliferation and dermoepidermal inflammation. Both factors may be influenced by magnetic fields, even if pertinent clinical and experimental data are not unequivocal. Our approach to this issue has involved the use of an easily found and applied magnetic source.
Methods. Five patients (aged 28 to 52; median: 38 years) affected by moderately severe plaque-type psoriasis were included in the study. Fourteen ellipsoid magnets (Magnetika™, Dual Sanitaly, Moncalieri, Italy) aligned in five parallel rows were applied to a single psoriatic plaque by means of an adhesive support; a controlateral symmetric psoriatic plaque was covered with an analogous device devoid of magnetism.
Results. In all cases the two plaques exhibited a mild clinical improvement after 1 and 2 weeks; however, no significant differences were found between the plaques submitted to a magnetic field and the controlateral control plaques.
Conclusions. The magnetic device used in the present study can improve the clinical features of psoriatic plaques just as much as a simple occlusion therapy; the weak magnetic fields produced by our device have been shown to be ineffective in the present study model. However, we cannot exclude that different types of magnetic fields (e.g. intermittent), with different intensities, and/or with different treatment procedures could have significant effects on psoriasis.