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Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Online ISSN 1827-1820
Bardazzi F., D’Acunto C., Raone B., Bianchi T.
Università degli Studi di Bologna Dipartimento di Medicina Clinica Specialistica e Sperimentale Sezione di Dermatologia (Responsabile: Prof. C. Varotti)
Bowen’s disease is a slowly progressive intraepithelial squamous cell carcinoma with highest incidence in the 50-69 years range. It occurs anywhere on the body surface, but the involvement of the nail bed epithelium is very rare. When the Bowen’s disease involves the nail bed epithelium it causes onycholysis. Ulceration, verrucous hyperplasia and fissures suggest the presence of an invasive squamous cell carcinoma. A 74-year-old female referred to us for a dystrophic nail plate and hypertrophical subungual tissue of the first finger of the right hand. She had been treated with electrosurgery for a subungual wart present since twenty years. A biopsy was performed and it revealed Bowen’s disease. The patient was submitted to cryosurgery. Follow-up of two years is negative. Histological examination is mandatory for diagnosis and biopsies, should be obtained from lesions of the nail bed which did not respond to treatment.