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Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Online ISSN 1827-1820
From the Clinica Dermatologica Università degli Studi - Genova
Scleromyxedema (SCL), considered to be the generalized and sclerodermoid subtype of lichen myxedematosus (papular mucinosis), is a disease with a chronic, progressive, and potentially disabling course. It is usually, although not invariably, associated with a monoclonal gammopathy which rarely leads to multiple myeloma and with many systemic manifestations. The therapy is difficult and the prognosis is guarded. The author, on the basis of literature and personal experience, review the anatomo-clinical manifestations of this uncommon disease.