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Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Online ISSN 1827-1820
Zumiani G., Zanoni M. *, Agostini G. **
Ospedale S. Maria del Carmine - UO Dermatologia Rovereto (Trento)
* Servizi Sanitari Terme di Comano - Comano (Trento)
** Università degli Studi - Pisa
Background. Psoriasis is a frequent genetic-induced chronic - relapsing, erythemato-squamous skin disease. Thermal bath therapy showed interesting results among the numerous possible therapies.
Methods. In order to verify this hypothesis, according to the National Health Government request (art. 2 D.M. 15-12-1994), a controlled randomized, double-blind clinical study was performed in Comano Thermal baths (Trento, Italy) with 50 psoriatic patients. Treatment consisted of 12 Comano-water thermal bath vs tap-water, with standard conditions of temperature and execution. Recruiting of patients was performed in Comano Thermal bahs according to inclusion criteria, with written informed consent. PASI index evaluated the clinical effectiveness and it was performed before and after 3 months of therapy. Hydration and sebum were measured before and after bath therapy.
Results. Clinical results showed improvement in 64.4% of Comano Thermal water treated patients and 11.5% tap-water treated patients (p<0.001). Very good results were obtained in 68% of patients (PASI index variation 50%). Hydration improved in bath therapy patients; sebum measurement showed no differences. Histologic reports showed a significant reduction of hyperkeratosis, acanthosis and papillomatosis. No undesired side-effects were described.
Conclusions. These results show the effectiveness of Comano Thermal water therapy in the treatment of psoriasis.