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Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Vergani R., Betti R., Tolomio E., Crosti C.
Università degli Studi - Milano, Clinica Dermatologica IV, Ospedale San Paolo - Milano
The pachydermodactyly is a non-frequent benign dermatosis belonging to the category of superficial fibromatosis. This disease affects particularly young males with a swelling of the lateral and dorsal surfaces of the proximal phalanges and of the proximal interphalangeal joints of the fingers of the hands. Usually bilateral, it involves the middle finger, the index finger and the ring finger very frequently, the little finger less frequently and the thumb as an exception. The pachydermodactyly has two variants: the monopachydermodactyly and the “pachydermodactyly transgrediens”. The pachydermodactyly is usually an acquired and, in the greatest part of the cases, a painless dermatosis. Moreover, it can sometimes be associated to other cutaneous or systemic diseases. In most of the cases the pachydermodactyly is due to unknown causes, though in some cases it is considered a psychocutaneous disorder or a microtraumatic dermatosis. From the histopathological point of view the pachydermodactyly is characterized by hyperplasia of the epidermis and by the increase in the number of collagen fibres in the dermis. The case of a 17-year-old boy affected by pachydermodactyly of the last four fingers of the left hand (unusual location) is described and a review of the cases published in the literature is presented, discussing the possible differential diagnoses with particular reference to the “knuckle pad”.