Advanced Search

Home > Journals > Giornale Italiano di Dermatologia e Venereologia > Past Issues > Giornale Italiano di Dermatologia e Venereologia 1999 December;134(6) > Giornale Italiano di Dermatologia e Venereologia 1999 December;134(6):565-70

ISSUES AND ARTICLES   MOST READ   eTOC

CURRENT ISSUEGIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA

A Journal on Dermatology and Sexually Transmitted Diseases

Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014

Frequency: Bi-Monthly

ISSN 0392-0488

Online ISSN 1827-1820

 

Giornale Italiano di Dermatologia e Venereologia 1999 December;134(6):565-70

    REVIEWS

Nail psoriasis therapy. Review of the literature

Forleo P. 1, Cerritelli L. 1, Feliciani C. 1, Koniger P. 1, Lo amerio P. 2, Proietto G. 1, Amerio P. 1

1 Clinica Dermatologica «G. D’Annunzio» - Chieti;
2 Clinica Dermatologica - Ancona

Incidence of nail involvement in psoriasis ranged, in the literature, from 10 to 55%. Therapy of nail psoriasis is often unsatisfying and great cooperation of patients is required. A great number of topical or systemic chemothetapies are reported in the literature such as: steroids, 5-fluorouracil, calcipotriol, PUVA-therapy, radiotherapy, methotrexate, retinoids, cyclosporin A. Topical steroids, 1% solution of 5-fluorouracil and systemic cyclosporin A, at this moment, seems to be the more effective drugs in nail psoriasis, but side effects are frequent due to their prolonged use in order to reduce relapse. Topical calcipotriol seems to be a promising treatment for subungueal hyperkeratosis and onycholysis especially on account of its high tolerability. Preliminary results about clinical trials of a combination of saystemic cyclosporin A and local application of calcipotriol are reported.

language: Italian


FULL TEXT  REPRINTS

top of page