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GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA

A Journal on Dermatology and Sexually Transmitted Diseases


Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
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Giornale Italiano di Dermatologia e Venereologia 1999 October;134(5):421-6

language: Italian

Skin diseases in 430 kidney transplant recipients

Lesnoni La Parola I. 1, Masini C. 1, Nanni G. 2, Diociaiuti A. 1, Capuano M. 1, Cerimele D. 1

1 Istituto di Clinica Dermatologica UCSC - Roma;
2 Centro Trapianti d’Organo UCSC - Roma


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Background. Cutaneous lesions can be a significant problem in kidney transplant recipients.
Methods. The incidence of iatrogenic, infectious and neoplastic skin diseases in 430 renal transplant recipients observed, from January 1988 to December 1997, at the Catholic University in Rome, is reported. All the patients were on therapy with cyclosporin and methylprednisone; just few patients had also azatioprine.
Results. Iatrogenic skin manifestations were the most common, followed by infections of the skin and neoplastic cutaneous lesions. The more frequent cutaneous infections are mycoses, particularly superficial dermatomycoses. Kaposi’s sarcoma represents the 50% of all the cutaneous neoplasms. In the group of patients studied, a low incidence of non-melanoma skin cancers and a normal BCC/SCC ratio were observed; it is suggested that an important point of preventive management is the education of patients to avoid UVR. In fact, shortly after transplantation, all patients receive advice on strict sun-avoidance, and use of a high factor UVA and UVB block.
Conclusions. In conclusion, this study underlines the importance of a continuous observation of every cutaneous lesions in renal transplant recipients.

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