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GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA

A Journal on Dermatology and Sexually Transmitted Diseases


Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
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Giornale Italiano di Dermatologia e Venereologia 1999 June;134(3):247-50

language: Italian

Uveomeningoencephalitis. A case report

Cattania M. 1, Fanti A. 2, Bisighini G. 1

1 Arcispedale «S. Maria Nuova» , Azienda Ospedaliera, Reggio Emilia, Servizio di Dermatologia;
2 Divisione Oculistica


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The authors report the rare case of a 44-year-old woman suffering from uveomeningoencephalitis. Clinical signs included: 1) uveitis with retinal detachment; 2) hypochromic maculae on the face; 3) alopecia areata on the scalp and 4) slight bilateral hearing loss for high frequencies. This syndrome may affect a number of systems: ocular, nervous, hearing and cutaneous. It is a rare condition in the white race and its etiopathogenesis is still uncertain. The most widely accredited hypothesis is that it is an autoimmune disease which affects genetically predisposed subjects, possibly triggered off by unknown viral agent.
Eye involvement, which is essential to diagnosis, may lead to severe complications for sight through recurrent episodes of uveitis. The authors underline the prognostic importance of correct steroid therapy, at an appropriate dose and continued for a sufficiently long period of time.

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