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Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Online ISSN 1827-1820
Università degli Studi -Catania, Clinica Dermatologica
Non-Hodgkin lymphomas are malignant neoplasms that are originated from cells of the lympho-reticular system and are three times more frequent than Hodgkin’s disease. The first mediastinal localization of a non-Hodgkin lymphoma causes a series of general and local symptoms are reported and explained. A case is described of a 24 year old female patient with a big mediastinal mass that has not given any characteristic symptomatology of this disease for about a year. A nodular skin lesion on the left lower part of the breast-bone was the first symptom. After extirpation of the nodular skin lesion, an ordinary histological exam has shown the malignant origin of the lesion because of the presence of big non-typical lymphoid cells. The inusual clinical presentation of a non-Hodgkin lymphoma with primary mediastinal localization together with the absence of any other general and local symptomatology is pointed out. Moreover, a very good response to polychemotherapy combined with radiotherapy whit a complete recovery and normal life of the patient after one year.