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GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA
A Journal on Dermatology and Sexually Transmitted Diseases
Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Giornale Italiano di Dermatologia e Venereologia 1999 February;134(1):53-5
Primary superficial leiomyosarcoma of the skin
Filosa G., Bugatti L., Nicolini M., Ciattaglia G.
Ospedale «A. Murri» - Jesi (Ancona), Divisione di Dermatologia
A case of a 66-year-old man suffering from a superficial cutaneous leiomyosarcoma of the right periareolar region is reported. This tumor developed from an asymptomatic nodule standing for 20 years, after the surgical removal of a colonic malignant neoplasia two years before. Superficial cutaneous LMS takes origin from the smooth muscle of the arrectores pilorum and must be differentiated from the deep form for the dermal localization, the low incidence of recurrence and extremely rare tendency to metastatize. In this case, the hypothesis is suggested that the reduced mechanisms of immunosurveilliance might explain the transformation of LMS from a benign cutaneous lesion at the same time of the onset of a visceral neoplasia.