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Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Online ISSN 1827-1820
Caccialanza M. 1, Dal Pozzo V. 2, Piccinno R. 1, Beretta M. 1, Gnecchi L. 1
1 From the Department of Photoradiotherapy, Ospedale Maggiore, IRCCS, Milan, University of Milan;
2 Dermatological Surgery, Institute of Dermatological Sciences, Ospedale Maggiore, IRCCS, Milan University of Milan
Background. Earlobe keloids are very frequent and often characterized by a peculiar clinical behaviour and response to therapy. They, represent a cosmetic problem, and may often cause pain to the patient as well. Aim of this study was to assess, through a retrospective study of our cases, the effectiveness and safety of postoperative radiotherapy performed in the period 1983-1996.
Methods. Seventeen patients affected by 20 keloid lesions were included in this study. Each lesion was histologically ascertained. Twelve were relapsing after previous non-radiological therapies. In 15 out of 17 cases radiotherapy was begun 7 days after surgery and performed with contact X-ray therapy (Chaoul). The total doses administered ranged from 20 to 30 Gy, by means of weekly fractions of 5 Gy each.
Results. The mean follow-up of the studied patient series was 64 months (range 7-146 months). Complete remission was obtained in the whole series (two lesions relapsed, but a new remission was obtained in one by means of corticosteroid injections and in the other by means of a new surgical excision followed by postoperative radiotherapy). The twenty-four month relapse-free rate after radiotherapy was 83.36%. The cosmetic results were judged as good in all cases. No complications and/or sequelae related to postoperative radiotherapy were observed.
Conclusions. The results obtained support that postoperative radiotherapy performed by means of skin diseases dedicated machines and with an integrate surgical-radiotherapic approach is an effective and safe treatment.