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Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Online ISSN 1827-1820
Bardazzi F., D'Acunto C., Landi C., Neri I.
Università degli Studi - Bologna, Clinica Dermatologica
A 67 year-old male developed pruritic, keratotic, papules within 6 months from starting maintenance hemodialysis. Clinically and histologically the papules showed the features of perforating folliculitis. Disorders of transepithelial elimination are not uncommon in patients on maintenance hemodialysis. Generally chronic renal failure is due to diabetic nephropathy, but in this patient it was secondary to a post-streptococcal nephropathy. The therapy of perforating folliculitis is difficult and often disappointing. This patient was non-responsive to topical corticosteroids and received UV-B phototherapy for a long period. The response to phototherapy was good but transitory: a remission of clinical findings and symptoms was achieved after each UV-B treatment without reaching a complete healing. The poor knowledge of pathogenesis and etiology of perforating folliculitis makes it difficult to choose an effective, pointed and resolutory therapy. The rule and the real effectiveness of phototherapy in our case is hard to define considering the relapsing natural course of the illness.