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Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Online ISSN 1827-1820
Mazzocchetti G., Ferrari A., Piccolo D., Peris K.
Università degli Studi - L’Aquila, Clinica Dermatologica
Background. Epiluminescence microscopy (ELM) is a noninvasive technique that uses the stereomicroscopy for in vivo clinical diagnosis of pigmented skin lesions. It is an interesting approach to this problem.
Methods. For this investigation, a stereomicroscope, a glass slide, and immersion oil are used. This technique considerably improves the accuracy of clinically diagnosed pigmented lesions. Specific epimicroscopic patterns that are not discerned by the naked eye can be correlated with well-defined histopathological structures. Diagnostic parameters were introduced as basic symptomatic features to allow the common use of this diagnostic tool.
Results. However, interpretation and reliability of the ELM criteria are still controversial. In the present study, cutaneous melanocytic and nonmelanocytic pigmented lesions of 143 patients were analyzed by epiluminescence microscopy; 78 pigmented skin lesions were studied: 17 dysplastic naevi, 15 junctional naevi, 12 dermal naevi, 7 seborrheic keratosis, 9 pigmented basal cell carcinoma and 18 hypopigmented dermal naevi. The purpose of this study was the use of three additional symptomatic parameters such as black lamella, exophytic papillary structures and telangiectases, which greatly enhance the diagnostic efficacy of this technique, are described in detail.
Conclusions. The results obtained suggest that ELM new citeria are useful to improve the accuracy of clinical diagnosis of these types of lesions.