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Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Online ISSN 1827-1820
Lavaroni G., Plozzer C., Torsello P., Kokelj F.
Università deglli Studi - Trieste, Istituto di Clinica Dermatologica
Background. Hallopeau’s acrodermatitis continua, which is considered a variant of pustolar psoriasis involving the extremities, has proved to be poorly sensitive to the various topical and systemic treatments.
Methods. Three patients who had been suffering from Hallopeau’s acrodermatitis for already six years are described. They came under observation for a marked worsening of the clinical picture; topical treatments (calcipotriol, steroids combined with keratolytics) as well as systemic treatments (etretinate, PUVA, Fans) had given poor results. In consideration of the great difficulties in their social life and work they have been treated them with cyclosporin A at the starting dose of 4 mg/kg per day.
Results. After two months of therapy (3 mg/kg per day) the clinical pictures showed a very good improvement and in one case a complete regression.
Conclusions. No side-effects were noted, confirming the efficacy and safety of cyclosporin A at low doses in the treatment of Hallopeau’s acrodermatitis.