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Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index
Online ISSN 1827-1782
Ergunes K., Yilik L., Yurekli I., Lafci B., Yasa H., Akyuz M., Celik E., Gurbuz A.
Departement of Cardiovascular Surgery Izmir Katip Çelebi University Atatürk Training and Research Hospital, Izmir, Turkey
Aim: Diabetes mellitus is an important risk factor for coronary artery disease. In this study, we investigated the effect of diabetes on in-hospital morbidity, mortality and survival in patients undergoing isolated on-pump CABG operation. we also investigated the effect of pre- and perioperative factors on in-hospital morbidity, mortality and survival.
Methods: Between January 2002 and December 2009, 1657 patients underwent isolated CABG in our clinic. Among these patients, 35.7% (n: 591) were diabetic, whereas 64.3% (n: 1066) were non-diabetic.
Results: Five independent predictive factors of in-hospital mortality rate in a multivariate regression analysis in patients with diabetes were identified, including prolonged cardiopulmonary bypass time (>3 h), prolonged operation time, prolonged ventilatory support, postoperative atrial fibrillation and postoperative renal insufficiency. In-hospital mortality rate was 8.1% (48) and 1.4% (15) in patients with and without diabetes, respectively (P=0.000). Length of intensive care unit and hospital stay were longer in patients with diabetes (P=0.000). Mean follow-up was 49.08±25.39 months and 47.79±25.06 months in patients with and without diabetes. Mid-term survival rate was 94.7% and 95% in patients with and without diabetes.
Conclusion: In-hospital mortality rate and morbidity rate were higher in patients with diabetes undergoing isolated on-pump CABG. Mid-term survival was similar in patients with and without diabetes.