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Chirurgia 2013 December;26(6):433-5

language: English

High-grade adenocarcinoma of the breast with squamous metaplasia: unusual intracystic localization

Accurso A. 1, Ciancia G. 2, Pettinato G. 2, Rocco N. 1

1 Department of General, Geriatric Oncologic Surgery and Advanced Technologies Faculty of Medicine and Surgery University Federico II of Naples, Naples, Italy;
2 Section of Pathologic Anatomy Department of Biomorphological and Functional Sciences Faculty of Medicine and Surgery University Federico II of Naples, Naples, Italy


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Adenosquamous carcinoma of the breast is a rare form of metaplastic breast carcinoma. We report an atypical case of high-grade adenosquamous carcinoma with unusual intracystic localization in a 36 years old woman. Imaging did not show characteristics of a clear malignant lesion (both US and mammography). High-grade intracystic adenosquamous carcinoma was treated with a quadrantectomy and sentinel node biopsy. The patient showed no distant metastasis at a one-year follow-up. Adenosquamous carcinoma of the breast is a rare form of metaplastic breast carcinoma. Intracystic localization results never reported before in medical literature. Data on correct management, follow-up and prognosis remain very limited, because of the paucity of reported cases.

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