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A Journal on Surgery

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Chirurgia 2013 June;26(3):245-7

language: Italian

Intraperitoneal chemotherapy in a patient with ovarian carcinoma associated with peritoneal carcinomatosis: the importance of intraoperative liver ultrasound

Bisogni D., Dioscoridi L., Bechi P.

Chirurgia Generale e d’Urgenza 2, AOUC, Firenze, Italia


HIPEC is the international acronym that identifies the hyperthermic intraperitoneal chemotherapy. It is used as a support for aggressive surgery of peritoneal carcinomatosis, with the primary aim of taking away the entire tumor mass macroscopically evident. The authors report the case of a patient 65 y.o. with bilateral ovarian invasive papillary serous carcinoma, associated with peritoneal carcinomatosis and suspicious hepatic metastasis of the II, III, IV, VIII segments on contrast-enhanced CT scan, then re-evaluated by intraoperative ultrasound, which put the diagnosis of angiomatous lesions. The patient was initially undergone to neoadjuvant chemotherapy (Carboplatin and Paclitaxel), and 5 months later, a bilateral hysterectomy and annessectomy, associated with appendectomy, omentectomy, surgical debulking of the mesentery, ileum, peritoneum of the pouch of Douglas, and intraoperative HIPEC were performed. At the last follow-up (6 months from the surgical operation), the patient has been free of disease, both from a clinical and instrumental point of view (CT with contrast medium).

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