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A Journal on Surgery

Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index

Frequency: Bi-Monthly

ISSN 0394-9508

Online ISSN 1827-1782


Chirurgia 2013 June;26(3):241-3


Arsenic necrosis in mucosa: an unusual case report

Koseoglu B. G., Kahraman N.

Department of Oral Surgery, Istanbul University, Istanbul, Turkey

Arsenic is one of the “tooth pulp devitalizing” agents used throughout dental history when anaesthesia was not available. Arsenic, is usually encountered in dentistry as its trioxide, a water-soluble compound, forming arsenious acid.Because of the potential for leakage, the use of arsenic oxide for devitalizing pulp was always unsafe. For this reason, and after improvements in local anaesthesia, the use of arsenical “devitalizing pastes” gradually declined.Arsenic and its compounds are known to be extremely toxic on contact with hard and soft tissues, and prolonged application or leakage of arsenic trioxide can cause severe damage to the periodontal tissues and alveolar bone. In this case report, the patient was 32 years-old man that he referred to our clinic because of the pain and wound in his right cheek mucosa. After revealing medical history, it was came out arsenic was used for pulp devitalization in his right maxillary first molar. We decided to take a soft tissue MR and operate him with laser. Until the operation day we adviced him liquid bepanthene mouthwash twice a day.Following 5 days, he made mouthwash and in control visit we saw that the wound healed.The patient has no more pain in his cheek. So the aim of this study is to report that arsenical pastes are stil employed in endodontics, to highlight the potentially serious censequences of their use and to show positive effect of bephanthene in soft tissue necrosis belong to arsenic.

language: English


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