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A Journal on Surgery
Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index
Chirurgia 2013 April;26(2):133-5
Deceased renal transplantation on a patient with sickle-cell nephropathy secondary to HbSC sickle cell disease
Giorgakis E., Cacciola R., Puliatti C.
Department of Transplantation and Vascular Access Surgery Royal London Hospital, Barts & The London NHS Trust London, UK
HbSC disease accounts for 20-30 % of sickle disease in African origin population. Chronic renal disease is present in 30% of these patients. Renal transplantation has the best long-term survival rate in end-stage sickle renal disease. Only a few renal transplantations on HbSC patients have been described worldwide. The current article describes the case of an end stage HbSC nephropathy patient undergoing renal transplantation from a non-heart-beating donor. Emphasis has been given to the description of the measures taken in order to prevent and minimize the deleterious effects of sickling in the peri-transplantation period.