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Chirurgia 2012 October;25(5):387-9

language: English

Epidural abscess with Aspergillus niger following cranioplasty

Satow T., Saiki M., Doi K.

Department of Neurosurgery, Shiga Medical Center for Adults, Moriyama, Japan


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We report a 71-year-old woman with epidural abscess with Aspergillus niger, six years after cranioplasty with polymethylmetacrylate. Surgery was conducted to remove the bone flap and close the frontal sinus with galeal flap. Postoperatively, irrigation took place with amphotericin B solution once a day for one week and intravenous administration of micafungin sodium for two weeks, followed by 6 months oral intake of itraconazole. This resulted in complete cure for follow-up of 5 years. This fungus can be a rare cause of postcranioplasty infection, successfully treated by surgery as well as irrigation with and systemic administration of antifungal agents.

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