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A Journal on Surgery

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Chirurgia 2012 June;25(3):217-20

language: English

Galbladder metastasis from renal cell carcinoma presenting as intraluminal polypoid mass and hemobilia: a case report

Valenti A. 1, 2, Gandini A. 1, Malerba M. 1, Meeus P. 1, Mithieux F. 1, 2

1 Department of Surgical Oncology,, Centre Léon Bérard, Lyon, France;
2 Institute of Experimental Surgery, Centre Léon Bérard, Lyon, France


Renal cell carcinoma is known for its ability to spread to other organs of the body. The most common metastatic sites are the lung and mediastinum (50%), bones (49%), skin (11%), liver (8%) and brain (3%). We report a rare case of a metachronous gallbladder metastasis in a 56-year old woman, diagnosed 10 years after the discovery of a left renal cell carcinoma. The lesion presented as an intraluminal polypoid mass with clinical features of hemobilia and anemia. In August 2006, the patient underwent typical cholecystectomy, which revealed a polypoid malignant lesion of 55 x 40 x 35 mm confined to the gallbladder mucosa with adherent blood clots. Histological examination confirmed the diagnosis of a polypoid submucosal metastasis from renal cell carcinoma. Cholecystectomy with intraoperative cholangiography was performed. The patient was followed every six months, and remained disease-free at two-year follow-up.

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