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Chirurgia 2012 April;25(2):145-9

language: English

Spontaneous regression of an interradicular radiolucency in the midline of the mandible: a case report

Yilmaz B., Ersev H., Dinçol M. E.

Department of Endodontics, Faculty of Dentistry, Istanbul University, Istanbul, Turkey


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The aim of this article was to report on the spontaneous regression of an interradicular radiolucency in the midline of the mandible, which is a rare phenomenon occurring in oral lesions. A 13-year-old girl was referred with the complaint of increased mobility of the lower central incisors. In the diagnostic radiograph, an ill-defined unilocular radiolucent lesion was detected between the central incisors. Periodontal probing did not show any attachment loss or bleeding. Electric and cavity tests revealed that the central incisors were vital. Prophylactic endodontic treatments of the central incisors were completed to ensure a comfortable field of surgery. Subsequently, the patient’s parents refused surgery (i.e., curettage of the lesion and biopsy) due to the possibility of losing the central incisors as well as for economic reasons. A radiograph taken after five months revealed that the lesion had regressed. One year later, the size of the lesion was stable. Our differential diagnosis included brown tumor of hyperparathyroidism, simple bone cyst, aneurysmal bone cyst, non-ossifying fibroma and central giant cell granuloma. A detailed literature review supports the opinion that this particular case may have involved a central giant cell granuloma. Differential diagnosis and possible spontaneous regression mechanisms are discussed for the present case.

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