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Chirurgia 2012 February;25(1:77-81

language: English

Primary diffuse large B-cell lymphoma presenting as a subdural tumor associated with calcified chronic subdural hematoma. Case report and review of the literature

Shimizu K., Ochiai M.

Department of Neurosurgery, Kyosai Tachikawa Hospital Federation National Public Service Personal Mutual Associations, Japan


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Non-Hodgkin’s lymphomas primarily harbored in the central nervous system (CNS) are rare. They commonly present as parenchymal mass lesions and their histological diagnoses are almost invariably diffuse large B-cell lymphomas, which are high-grade and aggressive tumors. Meningeal involvement is usually thought to be the spread of adjacent parenchymal lesions or the dissemination of systemic lymphoma. Primary meningeal tumors with the characteristics of typical CNS lymphomas are extremely rare. The authors present an unusual case of primary diffuse large B-cell lymphoma presenting as a space-occupying subdural mass, associated with calcified chronic subdural hematoma.

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