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A Journal on Surgery

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Chirurgia 2012 February;25(1):69-71

language: English

Supratentorial cortical/intra-axial anaplastic ependymoma with arachnoidal dissemination: clinical presentation, radiological and intraoperative findings. Case report and review of the literature

Kalfas F., Ronchini N., Godowicz T. T., Severi P.

Department of Neurological Surgery. Galliera Hospitals, Genoa, Italy


Ependymomas are WHO grade II-III neoplasms that occur commonly in the fourth ventricle, spinal cord and filum terminalis of children and young adults. They are usually solid contrast-enhancing lesions, but may also be cystic or calcified. Occasionally, ependymomas occur supratentorially in or near the third or lateral ventricles, and very rarely within the cerebral cortex or extraaxially (dural based). The authors present a rare case of cortical/intraaxial anaplastic ependymoma in a 56-year-old woman that clinically and radiographically mimicked other, most common lesions like brain metastasis and meningiomas. The patient presented with partial seizures and a not well-circumscribed left frontal, cortical-based mass with peripheral cystic component and edema with mass effect. A left frontal craniotomy was performed and the mass was gross totally resected. Histologically, the lesion demonstrated the features of grade III cellular ependymoma (anaplastic ependymoma). The postoperative course of the patient was uneventful. The patient underwent radiation therapy. No long-term follow-up is available.

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