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Chirurgia 2012 February;25(1):65-7

language: English

Unusual localization of primary large choroid plexus papilloma in an adult patient: clinical presentation, radiological findings and surgical management. Case report and review of the literature

Kalfas F., Ronchini N., Godowicz T. T., Severi P.

Department of Neurological Surgery, Galliera Hospitals, Genoa, Italy


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Choroid plexus papillomas are rare tumors that are confined to areas in which the choroid plexus is normally located. The most common site of presentation of these lesions is in the fourth ventricle in adults and lateral ventricles in children. The authors present the case of a 56-year-old-female who presented with a 3 month history of headache, nausea and gait ataxia. MRI demonstrated a homogeneously contrast-enhancing tumor filling the fourth ventricle and subsequent mild obstructive hydrocephalus. The tumor did not originate from the roof of the fourth ventricle as expected but from the ependymal lining covering the median rostral medulla near the pontomedullary junction. The patient underwent a suboccipital craniotomy and most of the tumor was excised. Magnetic resonance imaging 4 days after surgery confirmed the removal of the tumor with a thin strip of tissue remaining. Histological examination revealed a well-differentiated papillary choroid plexus papilloma with absence of anaplasia. After surgery the patient recovered well and was released in good condition with mild cerebellar gait disturbance.

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