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Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index
Online ISSN 1827-1782
Sanna S., Monteverde M., Mengozzi M., Taurchini M., Argnani D., Dell’Amore D.
Unit of Thoracic Surgery, Department of Thoracic Surgery, “G. B. Morgagni” Hospital, Forlì, Italy
Follicular dendritic cell sarcoma (FDCS) an extremely rare malignant tumour of unknown etiology which, owing to its heterogeneity, is not always easily recognized and thus accurately diagnosed and promptly treated. In fact this tumour may be misinterpreted in differential diagnosis as a form of metastatic carcinoma, ectopic thymoma or primary – metastatic malignant fibrous histiocytoma. To date there have only been 49 cases of FDCS reported in Literature. Superficial and deep lymph nodes are the most frequent sites for follicular cell sarcomas, but they also involved axillar and, more rarely, inguinal lymph nodes witth aspecific symptoms, and very rarely intra-abdominal structures. Mediastinal localization of this tumour is even more rare. An accurate diagnosis is very difficult and is obtained on surgical specimen only with immunohistochemical studies. The treatment of first choice for this pathology is surgical excision, whatever is the site of the lesion; radio - chemotherapy could be considered as adiuvant treatment of incomplete excisions or principal treatment of local recurrences or distant metastases, whose rates vary between 24 and 43% of cases. This combinated therapy seems to have good survival rates. We present a case of a 42 years old young man affected by mediastinal FDCS, surgically treated with complete excision of the mass.with good survival result.