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A Journal on Surgery

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Chirurgia 2010 December;23(6):311-3

language: English

Orofacial granulomatosis: a case report

Shetty D.C., Urs A.B., Rai H.C., Bablani D., Tyagi N.

Department of Oral and Maxillofacial Pathology I.T.S-CDSR, Muradnagar, India


Orofacial granulomatosis is an uncommon clinico-pathological entity describing patients who have oral lesions characterized by persistent and/or recurrent labial enlargement, oral ulcers and a variety of other orofacial features, who on lesional biopsy have lymphoedema and non-caseating granulomas. The aetiology of oral lesions with non-caseating granulomas includes oral Crohn’s disease (some patients with oral lesions will develop typical bowel symptoms of Crohn’s disease in ensuing months to years), tooth-associated infections, sarcoidosis and food or contact allergies. The present case report highlights a case of Orofacial granulomatosis in a forty year old female patient. The diagnostic approach for this condition has been given special importance, so as to aid in better patient management and prognosis. Treatment of orofacial granulomatosis is not reliably effective and may not be always necessary, although most patients do require some medical intervention.

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