Home > Journals > Chirurgia > Past Issues > Chirurgia 2010 October;23(5) > Chirurgia 2010 October;23(5):205-8





A Journal on Surgery

Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index



Chirurgia 2010 October;23(5):205-8

language: English

Cherubism: clinical case and genetic standpoints

Cantarelli Morosolli A. R. 1, Santiago Vale D. 2, Gallafassi D. 2, Niccoli-Filho W. 3

1 Stomatologic Clinic, School of Dentistry
Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil
2 Post Doctor Research Fellow
Department of Biosciences and Oral Diagnosis, Sao Paulo State University, School of Dentistry, Sao Jose dos Campos, Sao Paulo, Brazil
3 Head of Department of Biosciences and Oral Diagnosis, Sao Paulo State University
School of Dentistry, Sao Jose dos Campos
Sao Paulo, Brazil


Cherubism is a rare non-neoplastic hereditary disease, characterized by bilateral bone enlargement of the jaws and is accompanied by inflammation and fibrosis in childhood. An increase in jaw size is noted, with maximum enlargement occurring within 2 years of onset in most cases. By age 7, the lesions become static or progress relatively slowly until puberty. During the late teens, the disease may undergo spontaneous involution. The present case show a patient with history of bilateral enlargement of the jaw with the triad of clinical, histological and radiological findings that helps in the final diagnosis of cherubism.

top of page

Publication History

Cite this article as

Corresponding author e-mail