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CURRENT ISSUECHIRURGIA

A Journal on Surgery

Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index

Frequency: Bi-Monthly

ISSN 0394-9508

Online ISSN 1827-1782

 

Chirurgia 2010 October;23(5):151-4

    ORIGINAL ARTICLES

Gastric cancer in elderly:clinico-pathological features and surgical treatment

Guida F., Coppola Bottazzi E., Antonino A., Formisano G., Conte P., Avallone U.

Dipartimento di Chirurgia Generale, Geriatrica ed Endoscopia Diagnostica e Operativa, Università degli Studi di Napoli “Federico II” Napoli, Italia

Aim. The aim of this study was to analyze clinical and pathological features of gastric carcinoma in patients 70 an older with particular attention to the surgical treatment.
Methods. All patients who received a gastrectomy for adenocarcinoma in our surgical department since January 1998 to December 2002 were admitted to the study. Patients were divided into two groups for age: cut-off has been considered for 70 years old.
Results. 57 patients were admitted to the study : 41 were <70 years (range 37 – 70) and 16 patients were older (range 70 – 80). In the group of patients ≥ 70 years old gastric cancer was more frequent in male patients with a M/F ratio of 2,2 versus 1,05 in the younger group. <70 years old group there was a prevalent localization at the corpus (46,3% vs 18,7%); ≥ 70 years old group there was a greater prevalence of antral localizations (62,6% vs 39,1%). This pattern of distribution can explain the different surgical approach: infact <70 years old group there was a greater number of total gastrectomies (63,4% vs 38%);instead in the ≥ 70 years old group there was a greater number of subtotal gastrectomies (62% vs 36,6%). The group of patients aged 70 and older presented more comorbidities (81% vs 58,5%), but tumor-related deaths in the two groups were similar (61 % vs 62 %). In the ≥ 70 years old group there was a greater incidence of diffuse gastric cancer (44,8% vs 34,2%) with a greater neoplastic recurrence in this group (56,2% vs 44%).Different is also the recurrence pattern: <70 years old group there were more frequent locoregional recurrences (27% vs 12,5%);≥ 70 years old group there was a greater incidence of peritoneal (25% vs 2%) and hematogenous (18,7% vs 15%) recurrence.
Conclusions. Gastric cancer presents in the patient aged 70 and older: higher M/F ratio, more frequent antral localization, greater incidence of peritoneal and hematogenous recurrence. In addition, older patients often present more comorbidities and more pharmacological therapies. This is the reason why surgical approach should be modulated on the basis of the individual risk: age is nota contraindication for curative surgery as in our study tumor-related death is not different between the two groups.In addition, older patients usually have a reduced functional reserve, so a subtotal gastrectomy often results the best surgical approach for the greater incidence of antral tumors and the better quality of life for the presence of part of the stomach.

language: Italian


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