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A Journal on Surgery

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Chirurgia 2010 August;23(4):143-5

language: English

Segmental resection of the duodenum for gastrointestinal stromal tumor (GIST): report of a case

Pizzi M. 1, Pariani D. 2, Zetti G. 1, Bonifati L. 1, Samori G. 1

1 Azienda Ospedaliera Di Circolo di Busto Arsizio, Presidio di Saronno, U.O.C. Chirurgia Generale. Piazzale Borella, 1. 21047 Saronno, Varese, Italy
2 Azienda ospedaliera L. Sacco. U.O.C. Chirurgia Generale I Milan, Italy


We describe a case of a 41 year-old-man presented with acute upper gastrointestinal bleeding from a submucosal tumor located in the proximal part of the third portion of the duodenum, 3 cm distal of the Vater’s papilla. Surgical therapy was performed by segmental resection of the duodenum with a duodenojejunostomy. Histology revealed a GIST with a diameter of 7 cm and <5 mitoses/50 high power fields, indicating a low risk of malignancy. Therefore no adjuvant therapy with Imatinib was initiated. The postoperative course was uneventful, and five years after the operation the patient did not have any recurrence or metastatic tumor. This case report shows that GIST close to the ampulla of Vater can be treated successfully by partial resection of the duodenum instead of duodenopancreatectomy, which is correlated to an higher percentage of morbidity and mortality .

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