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Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index
Online ISSN 1827-1782
Dalio M.B. 1, Bredarioli M. 1, Muglia V.F. 2, Joviliano E.E. 3, Piccinato C.E. 4
1 Division of Vascular and Endovascular Surgery, Department of Surgery and Anatomy, Faculdade de Medicina de Ribeirão Preto
Universidade de São Paulo (FMRP-USP), Ribeirão Preto, SP, Brazil
2 Radiology, Department of Internal Medicine, FMRP-USP, Ribeirão Preto, SP, Brazil
3 Division of Vascular and Endovascular Surgery, Department of Surgery and Anatomy, FMRP-USP, Ribeirão Preto, SP, Brazil
4 Division of Vascular and Endovascular Surgery, Department of Surgery and Anatomy, FMRP-USP, Ribeirão Preto, SP, Brazil
Aim. The purpose of this study was to evaluate the effect of renal angioplasty alone and with stent on blood pressure control and maintenance of renal function.
Methods. We performed a retrospective review of patients submitted to renal angioplasty at our tertiary hospital between 1997 and 2007. Ambulatory values of systolic blood pressure (SBP), diastolic blood pressure (DBP), number of antihypertensive medications used (NM) and serum creatinine were recorded 2, 6, 12 and 18 months before and after the procedure. Outcomes for blood pressure control were determined comparing mean values of SBP, DBP and NM before angioplasty and during the follow-up. Outcomes for renal function were determined by plotting the inverse creatinine slope over time using breakpoint analysis.
Results. SBP, DBP and NM showed no significant variation between values before angioplasty and the follow-up ones. No patient was considered cured. For patients with baseline chronic renal insufficiency (serum creatinine >1.5 mg/dl), mean slope decreased from -0.0089 mg/dL/month to -0.0015 mg/dL/month, with p<0.05.
Conclusions. In patients with atherosclerotic renal artery stenosis, renal angioplasty alone and with stent had no benefit on blood pressure control, but when performed in patients with chronic renal insufficiency could slow renal function decrease.