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A Journal on Surgery

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Chirurgia 2009 December;22(6):263-8

language: Italian

Sinchronous and metachronous cancer

Berretta S. 1, Spartà D. 1, Fisichella R. 2, Bertino V. 1, Cimino E. 1, D’Agata A. 3, Berretta M. 4

1 Facoltà di Medicina e Chirurgia, Dipartimento di Chirurgia, U.O.C. di Clinica Chirurgica del P.O. S. Luigi, Università degli Studi di Catania, Catania
2 Dottorato di Ricerca “Approccio Oncologico Multimodale in età Geriatrica”, Università degli Studi di Catania, Catania
3 U.O. Chirurgia, ASL 7, Siena
4 Oncologia Medica, CRO, Aviano


The risk of second sincrhonous or metachronous primary tumour is frequently correlated to geriatric age, to recovery or to long survival after the treatment of the first cancer; the possible underlying mechanism of this association being a common carcinogenetic pathway : in fact, as carcinogenesis is a multistep time-requiring process, age is with no doubt the main risk factor for cancer. Therefore it’s expected that as people live longer they are more likely to develop cancer and of course the prevalence of multiple primary malignancies is destined to increase with age. Also the AA. discuss about their own experience and also they report 3 meaningful cases.

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