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Chirurgia 2008 April;21(2):63-5

language: Italian

Spinocellular carcinoma: clinical and epidemiological considerations and follow-up in 171 cases operated on at the Novara hospital

Choc I., Boriani F., Carlucci S., Bocchiotti M. A.

Istituto di Chirurgia Plastica Università di Torino, Torino, Italia


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Aim. Spinocellular carcinoma is a malignant tumour of the epidermis which reproduces the appearance of keratinising cells. In frequency terms it is the second most common tumour among malignant cutaneous neoplasias. Predisposing factors include a clear phototype, exposure to UV rays, ionising radiation and various chemical substances, burns, scarring, ulcers and genodermatosis.
Methods. Retrospective analysis of the clinical records of 171 patients, operated on for spinocellular carcinoma at the Dermatology Clinic of Novara Hospital from 1998 to 2004, took the following parameters into consideration: age and gender of the patients, localisation, histological type and degree of malignity of the tumour, type of exeresis carried out, alternative treatments (radiotherapy and chemotherapy), performance of controls, lymphnode or organ metastasis, recurrences, precancerous lesions, scarring or sensory sequelae, patients who passed away due to this specific pathology or for other reasons.
Results. Spinocellular carcinoma is a tumour typical of the elderly population (average age 74), especially male (67%), with localisation most commonly observed in the photo-exposed areas of the body (fronto-parieto-temporal region in 16.9% of cases), preceded in 17.5% of cases by actinic keratosis. Histological examination shows it to be moderately differentiated (G2) in 55% of cases. Lymphnode metastasis was seen in 1.1% and recurrences in 7.6%.
Conclusions. It is concluded that complete exeresis and Mohs micrographic surgery is required, especially in the case of recurrence. Prevention and early diagnosis, which can easily be carried out in a tumour that is mainly due to solar exposure, are fundamental.

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