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Chirurgia 2007 February;20(1):61-2

language: English

Prostate malacoplakia clinically mimicking adenocarcinoma. Case report and review of the literature

Galanakis I. 1, Papadopoulos G. 1, Stathouros G. 1, Liadakis G. 2, Tsonou A. 2, Lykourinas M. 1

1 Department of Urology Athens General Hospital “G. Gennimatas”, Athens, Greece
2 Department of Pathology Athens General Hospital “G. Gennimatas”, Athens, Greece


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Malacoplakia of the prostate is an extremely rare granulomatous inflammatory disorder, clinically and sonographically mimicking adenocarcinoma. The only way to establish an accurate diagnosis, avoiding that way a radical treatment for a rather benign disease, is the biopsy of the prostate under ultrasonic guidance and the thorough examination of the specimens. We report a case of malacoplakia of the prostate putting emphasis on its similarities to prostate carcinoma, regarding lack of clinical symptoms, highly elevated Prostate Specific Antigen, suspicious Digital Rectal Examination and hypoechoic area on Transrectal Ultrasound.

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