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A Journal on Surgery

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Chirurgia 2006 June;19(3):223-5

language: English

Surgical management of valvular heart disease associated with sickle cell anemia of HbD Los Angeles-type hemoglobinopathy

Bardakci H. 1, Vural K. 1, Kaplan S. 1, Astan A. 1, Yilmaz S. 2, Birincioglu L. 1

1 Department of Cardiovascular Surgery Yuksek Ihtisas Hospital of Turkey, Ankara, Turkey
2 Department of Hematology Yuksek Ihtisas Hospital of Turkey, Ankara, Turkey


Despite the major decline in the prevalence observed in many western populations, rheumatic heart valve disease is still a major public health problem in developing countries. Among the valvular heart surgery population, associated diseases which may hinder open-heart surgery are frequently encountered. Management of such conditions, sometimes becomes problematic due to our limited information or scarcity of reported experience about these problems. Like valvular diseases of rheumatic origin, hemoglobinopathies causing sickle cell anemia are relatively common in the Mediterranean region. In an effort to help accumulate our knowledge in the field, we report a unique case with sickle cell anemia related to a very rare hemoglobinopathy of Hb-D Los Angeles-type undergoing valvular heart surgery. To our knowledge, no cases with this disease that underwent surgical intervention have been reported.

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