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Chirurgia 2006 April;19(2):171-4

language: English

Left monolobar Caroli’s disease in adults: report 4 cases, one of these associated to cholangiocarcinoma

Guglielminetti D. 1, Zanzi F. 2, Guerra E. 3, Poddie D. B. 1

1 Department of Surgery, General Surgery Unit S.Maria delle Croci Hospital, Ravenna, Italy
2 Surgical Clinic, University of Ferrara, Italy
3 Surgical Clinic I, University of Bologna, Italy


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Caroli’s disease is a cystic expansion of hepatic biliary duct ,frequently shown with not specific pain symptomatology to the right abdominal quadrant, icterus and recurrent cholangitis, these ones hardly controllable with antibiotics therapy only. Cholangio RM is the most appropriate investigational methodical to diagnose the disease and to show the continuity of cystic expansion with biliary three. Authors report 4 cases of Caroli’s disease left epatectomy in adults, one of these associated to Cholangio-carcinoma. The patients have been were presenting abdominal pain in right hypochondrium and only one was showing it related to fever, in one case the diagnosis has been an occasional repert in a non symptomatic patient. When the disease is banished to one hepatic lobe only, the surgery resection is the most indicated election’s therapy to solve an eventual intrahepatic biliary lithiasis, potentials cholangitis, and the possible neoplastic risk. In the event of spreaded disease, the treatment includes endoscopic treatment, pharmacologic therapy and, at last, hepatic transplant.

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